PRP yakavimbika sei?
PRP inobata ne degranulation ye alpha particles mumaplatelet, ane zvimwe zvinokura zvinhu.PRP inofanira kugadzirirwa mune anticoagulant state uye inofanira kushandiswa mumagetsi, kuputika, kana maronda mukati memaminitsi e10 ekuvhara ropa.
Sezvo maplatelet achiitwa nekugwamba, kukura kwezvinhu zvinovanzwa kubva musero kuburikidza nesero membrane.Mukuita uku, ma alpha particles anovhengana kune platelet cell membranes, uye mapuroteni ekukura zvinhu anopedzisa bioactive mamiriro nekuwedzera histone uye carbohydrate parutivi cheni kune aya mapuroteni.
Zvidzidzo zvakaratidza kuti munhu mukuru mesenchymal stem masero, osteoblasts, fibroblasts, endothelial masero, uye epidermal masero anoratidza cell membrane receptors yekukura zvinhu muPRP.Aya ma-transmembrane receptors anozoita kuti aite activation ye endo native yemukati masaini mapuroteni anotungamira kune kutaura (kuvhura) kweakajairika cellular gene sequences, sekuwanda kwesero, matrix formation, osteoid formation, collagen synthesis, nezvimwe.
Nokudaro, PRP kukura zvinhu hazvimbopindi musero kana nucleus yayo, haisi mutagenic, inongowedzera kukurumidza kukurudzira kupora kwakajairika.
Mushure mekuputika kwekutanga kwePRP-yakabatana nekukura zvinhu, maplatelet anogadzira uye anobudisa zvimwe zvinhu zvekukura kwemazuva manomwe asara ehupenyu hwavo.Kana maplatelet apera uye afa, macrophages anosvika mudunhu kuburikidza neropa-anomutswa tsinga dzeropa dzinokura mukati kuti dzitore basa rekudzora maronda nekuvanza zvimwe zvakafanana zvekukura pamwe nezvimwe.Nokudaro, nhamba yemaplatelet ari mugraft, ronda, kana kuti ropa rakavharwa pajira rinotarisa kuti ronda racho rinokurumidza sei kupora.PRP inongowedzera kune iyo nhamba.
1) PRP inogona kukwidziridza masero emapfupa emapfupa muhombe pfupa uye mapfupa ekubatanidza uye kukurudzira kuumbwa kwemapfupa.PRP inewo zvakasiyana-siyana zvekukura zvinhu, izvo zvinogona kukurudzira kupatsanurwa kwesero uye kusiyanisa uye kukurudzira kugadziriswa kwemuviri.
2）Leukocyte muPRP inogona kuwedzera simba rekurwisa utachiona hwenzvimbo yakakuvara, kubatsira muviri kubvisa necrotic tishu, uye kukurumidze kugadzirisa kwekukuvara.
3）PRP ine huwandu hukuru hwefibrin, iyo inogona kuvaka iri nani kugadzirisa chikuva chekugadzirisa muviri uye kudonha maronda panguva imwe chete.
PRP yakachengeteka uye inoshanda here?
1)Autologous zvigadzirwa zveropa
Nhamba huru ye data yekuedza yakaratidza kuti PRP inogona kuratidza kuchengetedzwa kwayo uye kuvimbika mukurapa kwakawanda.Sechigadzirwa cheropa che autologous, PRP inonyatso kudzivirira kurambwa uye kutapurirana kwechirwere kunokonzerwa nekushandiswa kweropa reallogeneic panguva yekurapa.
2）Coagulation initiator yakachengeteka
PRP inoshandisa bovine thrombin seyekutanga coagulation, zvichiita kuti panguva imwe chete PRP iwedzere uye maitiro ekuvhiya.Iyo bovine thrombin inoshandiswa inopisa-inogadziriswa uye haikonzeri hutachiona.Uye nekuda kwekuti huwandu hwebovine thrombin hunoshandiswa hudiki, hahupindi mumuviri uye hunokonzera kurambwa panguva yekushandiswa.
3）Chigadzirwa chakachengeteka uye chinoshanda
Nzira dzeAseptic dzinoshandiswa mukugadzirira kwePRP, zvichiita kuti ropa rivhare risingakonzeri matambudziko ehutachiona uye harisi kukonzera bhakitiriya kukura.
(Zviri muchinyorwa ichi zvakadhindwa patsva, uye isu hatipe chero vimbiso yechokwadi, kuvimbika kana kuzara kwezviri muchinyorwa chino, uye hatina mhosva yemafungiro echinyorwa ichi, ndapota nzwisisa.)
Nguva yekutumira: Sep-14-2022